Data files are plotted the same in parametric and non-parametric mode. However, there is a difference in mixed function and data plots: in non-parametric mode with autoscaled x, the x range of the datafile controls the x range of the functions; in parametric mode it has no influence.
For completeness a last command set autoscale t is accepted. However, the effect of this "scaling" is very minor. When gnuplot determines that the t range would be empty, it makes a small adjustment if autoscaling is true. Otherwise, gnuplot gives an error. Such behavior may, in fact, not be very useful and the command set autoscale t is certainly questionable.
splot extends the above ideas as you would expect. If autoscaling is set, then x, y, and z ranges are computed and each axis scaled to fit the resulting data.